What is The Best Injection for Weight Loss in the UK?
If you’ve tried lifestyle changes, gym routines, and diet plans, but still struggle to lose weight, and now you are looking for the right weight loss injection — you’re in the perfect place for answers.
With the rising demand for medical weight loss injections in the UK, patients are often overwhelmed by the diversity of options and prices. They are also concerned about the effectiveness of different medications — which can leave them perplexed, unable to make an appropriate decision.
But there's nothing to worry: we're here to give a comprehensive comparison of different weight loss injections so you can make the right decision for yourself.
What are Weight Loss Injections?
Medical weight loss injections are treatments that mimic the process of naturally occurring hormones in your body for weight management. Most weight loss injections target GLP-1 receptors in the brain. GLP-1 is a gut hormone that is released by your small intestine as soon as food enters your body. It slows down digestion to slow gastric emptying, so you can feel full for longer.
The injections that fall into this category are:
Wegovy
Saxenda
Nevolat
Apart from these injections, Mounjaro is known for its dual-action nature: it targets both GLP-1 and GIP receptors in the brain.
Why People Are Turning to Weight Loss Injections
Weight Loss Injections are scientifically proven for weight loss, boosting the process compared to old methods.
Unlike traditional methods that rely on willpower alone, these treatments are clinically proven to enhance weight loss, especially when combined with lifestyle changes.
Every body is different with different needs and requirements. Your metabolism, hormone level, and health condition plays a role in weight loss.Yet traditional methods often treat everyone the same and expect identical results. But weight loss injections are designed to suit your biology, with treatment plans that can be adjusted and medically monitored for better results.
How Do Weight Loss Injections Work?
They essentially perform the following four functions in the body to control obesity:
Tells your brain you’re full: It sends a signal to the brain to stop eating by creating a sense of fullness.
Slows stomach emptying: It delays how quickly food leaves your stomach, helping you stay satisfied longer.
Controls blood sugar production: It tells your liver to stop making glucose when your blood sugar levels are already sufficient.
Boosts insulin release: It signals your pancreas to release insulin, which helps your body absorb and use glucose effectively.
What Are Some Popular Prescription Weight Loss Injections in the UK
Now that we’ve broken down how weight loss injections support your body on a biological level, let’s explore some of the most well-known options on the market.
Mounjaro
Mounjaro is a weekly weight loss injection that contains tirzepatide. Originally approved for diabetes, tirzepatide has shown powerful effects for weight loss, even at lower doses.
As mentioned before, Mounjaro sets itself apart with its dual action mechanism, targeting both GLP-1 and GIP receptors in the brain. This makes Mounjaro the most effective weight loss injection so far.
Being the most recently introduced treatment, Mounjaro has delivered impressive results in clinical trials, outperforming other options. However, it is still in the research and development phase for weight loss use in the UK.
Effectiveness
The starting dose of Mounjaro is 2.5 mg, which is gradually increased each week to reach the final dose of 10 mg or 15 mg, depending on your body’s response.
In clinical trials, patients using it have shown an average of 22.5% loss of their total body weight over 72 weeks, which is quite impressive and higher than other available options.
What is the Price Range
Mounjaro is available in the UK with prices ranging between £115 - 204.95 across different pharmacies.
Wegovy
Wegovy is also a weekly weight loss injection with Semaglutide as an active ingredient. Among available options, Wegovy is known for its high potency.
Dose & Effectiveness
It has a starting dose of 0.25 mg. Every week, the dose is increased gradually to reach the final dose of 2.4 mg.
In clinical trials, Wegovy is reported to have helped participants lose an average of 15% of total body weight over 68 weeks.
What is the Price Range?
Wegovy ranges between £99 – £250 across different pharmacies in the UK.
Nevolat & Saxenda
Nevolate & Saxenda are once-daily injections with liraglutide as an active ingredient.
Liraglutide is also used in diabetes treatment, but at a lower dose. For weight loss, it is formulated at a higher strength.
Dose & Effectiveness
Nevolat and Saxenda start at the dose of 0.6 mg and gradually increase each week to reach the final dose of 30 mg in the span of five weeks. This approach helps diminish side effects that are common at the start.
In clinical trials, liraglutide is reported to help patients lose an average of 8% of their body weight in the span of 56 weeks when paired with lifestyle changes.
What is the Price Range?
Saxenda is available across the UK with prices ranging from £95 - £399. While Nevolat price ranges between £64.99 - £199.99 at different pharmacies.
Key Differences Summarised
We have summarised key differences among popular weight loss injections in the following table:
Common Side Effects Of Weight Loss Injections
The common side effects of these weight loss injections may include:
Nausea
Vomiting
Constipation
Diarrhea
Bloating
Indigestion
Stomach pain or cramps
Gas and burping
Fatigue
Dizziness
Insomnia (reported by some users)
While nausea, bloating, and constipation are common across all options, Mounjaro users often report stronger appetite suppression, Wegovy users notice belching or headaches, and Saxenda/Nevolat users may experience milder but more recurring symptoms due to daily use.
What is the Right Weight Loss Injection For You?
There’s no one-size-fits-all answer when it comes to choosing a weight loss injection. Everyone’s body, lifestyle, and goals are different, and what works best for one person may not be ideal for another.
It’s important to critically analyse your lifestyle, understand the benefits and side effects of the injections, and consult your GP or clinician before starting any treatment.
If you lead a busy lifestyle, you may prefer weekly injections like Wegovy or Mounjaro, which offer convenience and fewer interruptions to your routine.
If you’re someone who prefers a consistent daily structure, a daily injection like Saxenda might help you stay more engaged and accountable throughout your journey.
For those who have underlying health conditions like type 2 diabetes, Mounjaro might serve dual purposes, helping with both weight and blood sugar management.
Ultimately, the right injection for you depends on your medical history, preferences, budget, and long-term weight management plan. Medical weight loss treatments are most effective when they’re aligned with your unique biological needs, lifestyle, and any underlying health conditions. Visit Mango Compare for more information.
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